

-Flexible & transparent
-Does not collpse
-Easy to suture (hydrogel)
-Consists of polysaccharides


WHAT IS CHITOSAN?
- Chitosan is a cationic polysaccharide of natural origin obtained by alkaline deacetylation of chitin.
- The chitin used in the production of Reaxon® tubes is of natural origin.
PROPERTIES OF CHITOSAN
- Bioactive – supports nerve regeneration equivalent to the autograf 4
- Antiadhesive – inhibits scar tissue and neurona formation 5
- Biocompatible – does not induce any immune response 6
- Antibacterial – limits infection risks 7
REAXON® NERVE REGROWTH AND PROTECTION TUBE ARE :
- Made of polysaccharides
- Resorbable 1
- Transparent
- Easy to suture (hydrogel)
/ REAXON® DIRECT – ULTRA FLEXIBLE PROTECTION TUBE
Intended for use in repair of peripheral nerve discontinuities in patients with completely separated nerves that are treated by end-to-end coaptation.

The diameter indicated is in a dry state. Once Reaxon® Direct has been soaked, its diameter increases up to 0,5 mm.
/ REAXON® NERVE GUIDE – NERVE REGROWTH TUBE
Intented for use in repair of peripheral nerve discontinuities in patients with completely separated nerves up to a nerve defect length of 26 mm.

The diameter indicated is in a dry state. Once Reaxon® Direct has been soaked, its diameter increases up to 0,5 mm.
1 Internal testingat Medovent : Reports RDV-001 and RDV-002
2 Internal testing at Medovent : Reports NG0064 and NG0090
3 Internal testing at Medovent : Reports NG0086
4 Haastert-Talini et al. Chitosan tubes of varying degrees of acetylation for bridging peripheral nerve defects. Biomaterials 2013; 34: 9886-9904
5 Marcol et al. Reduction of post-traumatic neuroma and epineural scar formation in rat sciatic nerve by application of microcrystallic chitosan. Microsurgery 2011; 31: 642-649
6 The biocompatibility of Reaxon® Nerve Guide has been proven in accordance with the ISO 10993 standards
7 Rabea et al. Chitosan as antimicrobial agent: application and mode of action. Biomacromolecules 2003; 4: 1457-1465
Note : Bench testing is not necessarily indicative of clinical performance